Inclusion complex of S(-) bupivacaine and 2-hydroxypropyl- -cyclodextrin: study of morphology and cytotoxicity

• Main Authors: C.M. Moraes (Author), D.R. Araújo (Author), M.G. Issa (Author), H.G. Ferraz (Author), F. Yokaichiya (Author), M.K.K.D. Franco (Author), I. Mazzaro (Author), P.S. Lopes (Author), M.M. Gonçalves (Author), E. de Paula (Author), L.F. Fraceto (Author)
• Format: Book
• Published: São Paulo State University (UNESP), 2006-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Local anesthetics (LA) belong to a class of pharmacological compounds that attenuate or eliminate pain by binding to the sodium channel of excitable membranes, blocking the influx of sodium ions and the propagation of the nerve impulse. S (-) bupivacaine (S(-) bvc) is a local anesthetic of amino-ami...