Gene expression databases for physiologically based pharmacokinetic modeling of humans and animal species

• Asıl Yazarlar: Henrik Cordes (Yazar), Hermann Rapp (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2023-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract In drug research, developing a sound understanding of the key mechanistic drivers of pharmacokinetics (PK) for new molecular entities is essential for human PK and dose predictions. Here, characterizing the absorption, distribution, metabolism, and excretion (ADME) processes is crucial for...