Scale-up synthesis of TAP7f, an antitumoral triazolyl peptidyl penicillin

• Glavni avtor: Patricia Griselda Cornier (Author)
• Format: Knjiga
• Izdano: Facultad de Farmacia, Universidad de Granada, 2020-08-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Purpose: The purpose of this work was to develop a synthetic process to obtain the compound with anti-tumor activity, TAP7f, on a gram scale, for preclinical studies. Method: Solution chemistry strategies were used to replace the original synthetic solid phase route to make the process more...