Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds

• Main Authors: Yang Wu (Author), Chun Zhang (Author), Mei Guo (Author), Weikang Hu (Author), Yangling Qiu (Author), Mengran Li (Author), Dong Xu (Author), Pengfei Wu (Author), Jing Sun (Author), Run Shi (Author), Zili Zhang (Author), Kuirong Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic pancreatitis (CP) is a precancerous illness linked to pancreatic ductal adenocarcinoma (PDAC), although the evolutionary mechanism is uncertain. CP is distinguished by severe fibrosis caused by the activation of pancreatic stellate cells (PSCs). The current clinical therapeutic protocol for...