A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

• Main Authors: Leslie Renee Cockerham (Author), Steven A. Yukl (Author), Kara Harvill (Author), Ma Somsouk (Author), Sunil K. Joshi (Author), Elizabeth Sinclair (Author), Teri Liegler (Author), Rebecca Hoh (Author), Sophie Lyons (Author), Peter W. Hunt (Author), Adam Rupert (Author), Irini Sereti (Author), David R. Morcock (Author), Ajantha Rhodes (Author), Claire Emson (Author), Marc K. Hellerstein (Author), Jacob D. Estes (Author), Sharon Lewin (Author), Steven G. Deeks (Author), Hiroyu Hatano (Author)
• Format: Book
• Published: Case Western Reserve University, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and whether this le...