Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

• Главные авторы: Marie Joyeux-Faure (Автор), Renaud Tamisier (Автор), Jean-Philippe Baguet (Автор), Sonia Dias-Domingos (Автор), Stephen Perrig (Автор), Georges Leftheriotis (Автор), Jean-Paul Janssens (Автор), Wojciech Trzepizur (Автор), Sandrine H. Launois (Автор), Françoise Stanke-Labesque (Автор), Patrick A. Lévy (Автор), Frédéric Gagnadoux (Автор), Jean-Louis Pepin (Автор)
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• Опубликовано: Hindawi Limited, 2014-01-01T00:00:00Z.
• Предметы: article
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Rationale. Accumulated evidence implicates sympathetic activation as inducing oxidative stress and systemic inflammation, which in turn lead to hypertension, endothelial dysfunction, and atherosclerosis in obstructive sleep apnea (OSA). Statins through their pleiotropic properties may modify inflamm...