RU486 Metabolite Inhibits CCN1/Cyr61 Secretion by MDA-MB-231-Endothelial Adhesion

• Main Authors: Suhong Yu (Author), Cuicui Yan (Author), Wenjing Wu (Author), Sudan He (Author), Min Liu (Author), Jian Liu (Author), Xingtian Yang (Author), Ji Ma (Author), Yusheng Lu (Author), Lee Jia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Successful adhesion of circulating tumor cells (CTCs) to microvascular endothelium of distant metastatic tissue is the key starting step of metastatic cascade that could be effectively chemoprevented as we demonstrated previously. Here, we hypothesize that the hetero-adhesion may produce secretory b...