Systems biology reveals anatabine to be an NRF2 activator

• Egile Nagusiak: Dimitris E. Messinis (Egilea), Carine Poussin (Egilea), Diogo A. R. S. Latino (Egilea), Yvan Eb-Levadoux (Egilea), Remi Dulize (Egilea), Dariusz Peric (Egilea), Emmanuel Guedj (Egilea), Bjoern Titz (Egilea), Nikolai V. Ivanov (Egilea), Manuel C. Peitsch (Egilea), Julia Hoeng (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Anatabine, an alkaloid present in plants of the Solanaceae family (including tobacco and eggplant), has been shown to ameliorate chronic inflammatory conditions in mouse models, such as Alzheimer's disease, Hashimoto's thyroiditis, multiple sclerosis, and intestinal inflammation. However,...