Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants

• Main Authors: Chunsheng Wu (Author), Xiangting Yi (Author), Renzhi Xu (Author), Maokuan Zhang (Author), Yan Xu (Author), Yan Ma (Author), Li Gao (Author), Zhengbao Zha (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Etoposide (VP16) is the traditional antitumor agent which has been widely used in a variety of cancers. However, intravenous administration of VP16 was limited in clinical application because of its low aqueous solubility, poor bioavailability and dose-limiting adverse effects. Local chemotherapy wi...