Toward mechanistic medical digital twins: some use cases in immunology

• Main Authors: Reinhard Laubenbacher (Author), Fred Adler (Author), Gary An (Author), Filippo Castiglione (Author), Stephen Eubank (Author), Luis L. Fonseca (Author), James Glazier (Author), Tomas Helikar (Author), Marti Jett-Tilton (Author), Denise Kirschner (Author), Paul Macklin (Author), Borna Mehrad (Author), Beth Moore (Author), Virginia Pasour (Author), Ilya Shmulevich (Author), Amber Smith (Author), Isabel Voigt (Author), Thomas E. Yankeelov (Author), Tjalf Ziemssen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A fundamental challenge for personalized medicine is to capture enough of the complexity of an individual patient to determine an optimal way to keep them healthy or restore their health. This will require personalized computational models of sufficient resolution and with enough mechanistic informa...