<i>Harpagophytum procumbens</i> Root Extract Mediates Anti-Inflammatory Effects in Osteoarthritis Synoviocytes through CB2 Activation

• Main Authors: Alessia Mariano (Author), Irene Bigioni (Author), Roberto Mattioli (Author), Antonella Di Sotto (Author), Martina Leopizzi (Author), Stefania Garzoli (Author), Pier Francesco Mariani (Author), Pietro Dalla Vedova (Author), Sergio Ammendola (Author), Anna Scotto d'Abusco (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The endocannabinoid system is involved in the nociceptive and anti-inflammatory pathways, and a lowered expression of CB2 receptors has been associated with inflammatory conditions, such as osteoarthritis (OA). This suggests that CB2 modulators could be novel therapeutic tools to treat OA. In the pr...