Cardiac alterations in human African trypanosomiasis (T.b. gambiense) with respect to the disease stage and antiparasitic treatment.

• Main Authors: Johannes A Blum (Author), Caecilia Schmid (Author), Christian Burri (Author), Christoph Hatz (Author), Carol Olson (Author), Blaise Fungula (Author), Leon Kazumba (Author), Patrick Mangoni (Author), Florent Mbo (Author), Kambau Deo (Author), Alain Mpanya (Author), Amadeo Dala (Author), Jose R Franco (Author), Gabriele Pohlig (Author), Michael J Zellweger (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds are desperately needed. Evaluation of cardiotoxicity is one parameter of drug safety, but without knowledge of t...