Targeting Lactate Dehydrogenase-B as a Strategy to Fight Cancer: Identification of Potential Inhibitors by In Silico Analysis and In Vitro Screening
Lactate dehydrogenase (LDH) is an enzyme that catalyzes the reversible conversion of lactate to pyruvate while reducing NAD<sup>+</sup> to NADH (or oxidizing NADH to NAD<sup>+</sup>). Due to its central role in the Warburg effect, LDH-A isoform has been considered a promising...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2023-10-01T00:00:00Z.
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