Targeting Lactate Dehydrogenase-B as a Strategy to Fight Cancer: Identification of Potential Inhibitors by In Silico Analysis and In Vitro Screening

Lactate dehydrogenase (LDH) is an enzyme that catalyzes the reversible conversion of lactate to pyruvate while reducing NAD<sup>+</sup> to NADH (or oxidizing NADH to NAD<sup>+</sup>). Due to its central role in the Warburg effect, LDH-A isoform has been considered a promising...

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Main Authors: Manos Vlasiou (Author), Vicky Nicolaidou (Author), Christos Papaneophytou (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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