Scabronine G Methyl Ester Improves Memory-Related Behavior and Enhances Hippocampal Cell Proliferation and Long-Term Potentiation via the BDNF-CREB Pathway in Olfactory Bulbectomized Mice

• Main Authors: Osamu Nakagawasai (Author), Jia-Rong Lin (Author), Takayo Odaira (Author), Kohei Takahashi (Author), Wataru Nemoto (Author), Shigeki Moriguchi (Author), Yasushi Yabuki (Author), Yu Kobayakawa (Author), Kohji Fukunaga (Author), Masahisa Nakada (Author), Koichi Tan-No (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A previous study reported that scabronine G methyl ester (SG-ME) potentially enhances the in vitro secretion of neurotrophic factors such as nerve growth factor via the protein kinase C (PKC)-ζ pathway. However, it remains unknown whether SG-ME can improve cognitive dysfunctions in olfactory bulbect...