Genetic ablation of CXCR2 protects against cigarette smoke-induced lung inflammation and injury

• Autors principals: Chad A Lerner (Autor), Lei Wei (Autor), Isaac Kirubakaran Sundar (Autor), Irfan Rahman (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Antagonism of CXCR2 receptors, predominately located on neutrophils and critical for their immunomodulatory activity, is an attractive pharmacological therapeutic approach aimed at reducing the potentially damaging effects of heightened neutrophil influx into the lung caused by environmental agents...