Macrophage P2X7 Receptor Function Is Reduced during Schistosomiasis: Putative Role of TGF-β1

• Main Authors: Suellen D'arc Santos Oliveira (Author), Hayandra Ferreira Nanini (Author), Luiz Eduardo Baggio Savio (Author), Mariana Caldas Waghabi (Author), Claudia Lucia Martins Silva (Author), Robson Coutinho-Silva (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis is a chronic inflammatory disease whose macrophages are involved in immunopathology modulation. Although P2X7 receptor signaling plays an important role in inflammatory responses mediated by macrophages, no reports have examined the role of P2X7 receptors in macrophage function durin...