Optimisation of Solid-Phase Extraction and LC-MS/MS Analysis of Six Breast Cancer Drugs in Patient Plasma Samples

• Main Authors: Lu Turković (Author), Dragana Mutavdžić Pavlović (Author), Zvonimir Mlinarić (Author), Anamarija Skenderović (Author), Tajana Silovski (Author), Miranda Sertić (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the development of bioanalytical LC-MS methods for the determination of drugs in plasma samples in a clinical setting, adequate sample preparation is of utmost importance. The main goals are to achieve the selective extraction of the analytes of interest and attain thorough matrix removal while r...