Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγnull mice

• Main Authors: Barbara Ghinassi (Author), Leda Ferro (Author), Francesca Masiello (Author), Valentina Tirelli (Author), Massimo Sanchez (Author), Giovanni Migliaccio (Author), Carolyn Whitsett (Author), Stefan Kachala (Author), Isabelle Riviere (Author), Michel Sadelain (Author), Anna Rita Migliaccio (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ex vivo expanded erythroblasts (EBs) may serve as advanced transfusion products provided that lodgment occurs in the macrophage-niche of the marrow permitting maturation. EBs expanded from adult and cord blood expressed the receptors (CXCR4, VLA-4, and P-selectin ligand 1) necessary for interaction...