Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord

• Main Authors: Uta Daisuke (Author), Kawamata Tomoyuki (Author), Furue Hidemasa (Author), Yanagisawa Yoshikazu (Author), Yamamoto Jun (Author), Furuse Shingo (Author), Katafuchi Toshihiko (Author), Imoto Keiji (Author), Iwamoto Yukihide (Author), Yoshimura Megumu (Author)
• Format: Book
• Published: SAGE Publishing, 2010-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Chronic bone cancer pain is thought to be partly due to central sensitization. Although murine models of bone cancer pain revealed significant neurochemical changes in the spinal cord, it is not known whether this produces functional...