Rapamycin Attenuated Cardiac Hypertrophy Induced by Isoproterenol and Maintained Energy Homeostasis via Inhibiting NF-κB Activation

• Main Authors: Xi Chen (Author), Siyu Zeng (Author), Jian Zou (Author), Yanfang Chen (Author), Zhongbao Yue (Author), Ying Gao (Author), Luankun Zhang (Author), Weiwei Cao (Author), Peiqing Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rapamycin, also known as sirolimus, is an immunosuppressant drug used to prevent rejection organ (especially kidney) transplantation. However, little is known about the role of Rapa in cardiac hypertrophy induced by isoproterenol and its underlying mechanism. In this study, Rapa was administrated in...