Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis

• Main Authors: Nobutaka Takeda (Author), Atsunori Tsuchiya (Author), Masaki Mito (Author), Kazuki Natsui (Author), Yui Natusi (Author), Yohei Koseki (Author), Kei Tomiyoshi (Author), Fusako Yamazaki (Author), Yuki Yoshida (Author), Hiroyuki Abe (Author), Masayuki Sano (Author), Taketomo Kido (Author), Yusuke Yoshioka (Author), Junichi Kikuta (Author), Tohru Itoh (Author), Ken Nishimura (Author), Masaru Ishii (Author), Takahiro Ochiya (Author), Atsushi Miyajima (Author), Shuji Terai (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The progression of liver fibrosis leads to portal hypertension and liver dysfunction. However, no antifibrotic agents have been approved for cirrhosis to date, making them an unmet medical need. Small extracellular vesicles (sEVs) of mesenchymal stem cells (MSCs) are among these...