Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers

• Main Authors: Sadia Tabassam Arif (Author), Shahiq uz Zaman (Author), Muhammad Ayub Khan (Author), Tanveer A. Tabish (Author), Muhammad Farhan Sohail (Author), Rabia Arshad (Author), Jin-Ki Kim (Author), Alam Zeb (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study is aimed to develop and optimize levosulpiride-loaded nanostructured lipid carriers (LSP-NLCs) for improving oral bioavailability and prokinetic activity of LSP. LSP-NLCs were optimized with D-optimal mixture design using solid lipid, liquid lipid and surfactant concentrations as i...