Decursinol-mediated antinociception and anti-allodynia in acute and neuropathic pain models in male mice: Tolerance and receptor profiling

• Main Authors: LaTaijah C. Crawford (Author), Sangyub Kim (Author), Deepkamal Karelia (Author), Diana E. Sepulveda (Author), Daniel J. Morgan (Author), Junxuan Lü (Author), Angela N. Henderson-Redmond (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Korean scientists have shown that oral administration of Angelica gigas Nakai (AGN) root alcoholic extract and the metabolite of its pyranocoumarins, decursinol, have antinociceptive properties across various thermal and acute inflammatory pain models. The objectives of this study were 1) to assess...