Decursinol-mediated antinociception and anti-allodynia in acute and neuropathic pain models in male mice: Tolerance and receptor profiling

• Ngā kaituhi matua: LaTaijah C. Crawford (Author), Sangyub Kim (Author), Deepkamal Karelia (Author), Diana E. Sepulveda (Author), Daniel J. Morgan (Author), Junxuan Lü (Author), Angela N. Henderson-Redmond (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Korean scientists have shown that oral administration of Angelica gigas Nakai (AGN) root alcoholic extract and the metabolite of its pyranocoumarins, decursinol, have antinociceptive properties across various thermal and acute inflammatory pain models. The objectives of this study were 1) to assess...