Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• المؤلفون الرئيسيون: Giulio Poli (مؤلف), Salvatore Galati (مؤلف), Adriano Martinelli (مؤلف), Claudiu T. Supuran (مؤلف), Tiziano Tuccinardi (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...