Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Prif Awduron: Giulio Poli (Awdur), Salvatore Galati (Awdur), Adriano Martinelli (Awdur), Claudiu T. Supuran (Awdur), Tiziano Tuccinardi (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...