Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Main Authors: Giulio Poli (Author), Salvatore Galati (Author), Adriano Martinelli (Author), Claudiu T. Supuran (Author), Tiziano Tuccinardi (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...