Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Hauptverfasser: Giulio Poli (Verfasst von), Salvatore Galati (Verfasst von), Adriano Martinelli (Verfasst von), Claudiu T. Supuran (Verfasst von), Tiziano Tuccinardi (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...