Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Κύριοι συγγραφείς: Giulio Poli (Συγγραφέας), Salvatore Galati (Συγγραφέας), Adriano Martinelli (Συγγραφέας), Claudiu T. Supuran (Συγγραφέας), Tiziano Tuccinardi (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...