Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Autores principales: Giulio Poli (Autor), Salvatore Galati (Autor), Adriano Martinelli (Autor), Claudiu T. Supuran (Autor), Tiziano Tuccinardi (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...