Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Egile Nagusiak: Giulio Poli (Egilea), Salvatore Galati (Egilea), Adriano Martinelli (Egilea), Claudiu T. Supuran (Egilea), Tiziano Tuccinardi (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...