Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Autori principali: Giulio Poli (Autore), Salvatore Galati (Autore), Adriano Martinelli (Autore), Claudiu T. Supuran (Autore), Tiziano Tuccinardi (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...