Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• 主要な著者: Giulio Poli (著者), Salvatore Galati (著者), Adriano Martinelli (著者), Claudiu T. Supuran (著者), Tiziano Tuccinardi (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...