Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

• Үндсэн зохиолчид: Giulio Poli (Зохиогч), Salvatore Galati (Зохиогч), Adriano Martinelli (Зохиогч), Claudiu T. Supuran (Зохиогч), Tiziano Tuccinardi (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...