ATP Modifies the Proteome of Extracellular Vesicles Released by Microglia and Influences Their Action on Astrocytes

• Main Authors: Francesco Drago (Author), Marta Lombardi (Author), Ilaria Prada (Author), Martina Gabrielli (Author), Pooja Joshi (Author), Dan Cojoc (Author), Julien Franck (Author), Isabelle Fournier (Author), Jacopo Vizioli (Author), Claudia Verderio (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular ATP is among molecules promoting microglia activation and inducing the release of extracellular vesicles (EVs), which are potent mediators of intercellular communication between microglia and the microenvironment. We previously showed that EVs produced under ATP stimulation (ATP-EVs) p...