Intravenous injection of a novel viral immunotherapy encoding human interleukin-7 in nonhuman primates is safe and increases absolute lymphocyte count

• Main Authors: Charles-Antoine Coupet (Author), Clarisse Dubois (Author), Alexeï Evlachev (Author), Nadine Kehrer (Author), Marie Baldazza (Author), Sam Hofman (Author), Michel Vierboom (Author), Perrine Martin (Author), Geneviève Inchauspe (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Persistence of an immunosuppression, affecting both the innate and adaptive arms of the immune system, plays a role in sepsis patients' morbidity and late mortality pointing to the need for broad and effective immune interventions. MVA-hIL-7-Fc is a non-replicative recombinant Modified Vaccinia...