A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects

Abstract This study aimed to define the clinically relevant supratherapeutic dose of rilzabrutinib, an oral Bruton tyrosine kinase (BTK) inhibitor, and evaluate potential effects of therapeutic and supratherapeutic exposures on cardiac repolarization in healthy subjects. This was a two‐part phase I...

Olles dieđut

Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Sibel Ucpinar (Dahkki), Borje Darpo (Dahkki), Ann Neale (Dahkki), Philip Nunn (Dahkki), Jin Shu (Dahkki), Katherine A. Chu (Dahkki), Marianne Kavanagh (Dahkki), Hongqi Xue (Dahkki), Pasit Phiasivongsa (Dahkki), Dolca Thomas (Dahkki), Patrick F. Smith (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: Wiley, 2022-06-01T00:00:00Z.
Fáttát:
Liŋkkat:Connect to this object online.
Fáddágilkorat: Lasit fáddágilkoriid
Eai fáddágilkorat, Lasit vuosttaš fáddágilkora!

Interneahtta

Connect to this object online.

3rd Floor Main Library

oažžasuvvan: 3rd Floor Main Library
Hildobáiki: A1234.567
Njađus 1 Oažžumis