Glial expression of Swiss cheese (SWS), the Drosophila orthologue of neuropathy target esterase (NTE), is required for neuronal ensheathment and function

• Main Authors: Sudeshna Dutta (Author), Franziska Rieche (Author), Nina Eckl (Author), Carsten Duch (Author), Doris Kretzschmar (Author)
• Format: Bog
• Udgivet: The Company of Biologists, 2016-03-01T00:00:00Z.
• Fag: article
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Mutations in Drosophila Swiss cheese (SWS) or its vertebrate orthologue neuropathy target esterase (NTE), respectively, cause progressive neuronal degeneration in Drosophila and mice and a complex syndrome in humans that includes mental retardation, spastic paraplegia and blindness. SWS and NTE are...