High expression of insulinoma‐associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin

• Main Authors: Anne‐Sophie Litmeyer (Author), Björn Konukiewitz (Author), Atsuko Kasajima (Author), Sebastian Foersch (Author), Felix Schicktanz (Author), Maxime Schmitt (Author), Franziska Kellers (Author), Albert Grass (Author), Paul Jank (Author), Bettina Lehman (Author), Thomas M Gress (Author), Anja Rinke (Author), Detlef K Bartsch (Author), Carsten Denkert (Author), Wilko Weichert (Author), Günter Klöppel (Author), Moritz Jesinghaus (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Complementary to synaptophysin and chromogranin A, insulinoma‐associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in conventional colorectal adenocarcinomas (CRCs) and co...