Formulation and Characterization of Ursodeoxycholic Acid Nanosuspension Based on Bottom-Up Technology and Box-Behnken Design Optimization

Formulation and Characterization of Ursodeoxycholic Acid Nanosuspension Based on Bottom-Up Technology and Box-Behnken Design Optimization

Background: Ursodeoxycholic acid (UDCA) is a therapeutic agent used for the treatment of cholestatic hepatobiliary diseases in pediatric patients. It is a bile acid that presents high lipophilicity, and it belongs to Class II of the Biopharmaceutical Classification System (BCS), which exhibits low w...

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Main Authors: Oriana Boscolo (Author), Sabrina Flor (Author), Leandro Salvo (Author), Cecilia Dobrecky (Author), Christian Höcht (Author), Valeria Tripodi (Author), Marcela Moretton (Author), Silvia Lucangioli (Author)
Format: Book
Published: MDPI AG, 2023-07-01T00:00:00Z.
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