Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis

• Main Authors: Sungyoung Lee (Author), Sunmee Kim (Author), Yongkang Kim (Author), Bermseok Oh (Author), Heungsun Hwang (Author), Taesung Park (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Backgrounds Recent large-scale genetic studies often involve clustered phenotypes such as repeated measurements. Compared to a series of univariate analyses of single phenotypes, an analysis of clustered phenotypes can be useful for substantially increasing statistical power to detect more...