Th1-biased immunomodulation and therapeutic potential of Artemisia annua in murine visceral leishmaniasis.

• Main Authors: Mohammad Islamuddin (Author), Garima Chouhan (Author), Abdullah Farooque (Author), Bilikere S Dwarakanath (Author), Dinkar Sahal (Author), Farhat Afrin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:In the absence of vaccines and limitations of currently available chemotherapy, development of safe and efficacious drugs is urgently needed for visceral leishmaniasis (VL) that is fatal, if left untreated. Earlier we reported in vitro apoptotic antileishmanial activity of n-hexane fracti...