Suppression of ferroptosis through the SLC7A11/glutathione/glutathione peroxidase 4 axis contributes to the therapeutic action of the Tangshenning formula on diabetic renal tubular injury

• Main Authors: Xiao-Meng Shan (Author), Chun-Wei Chen (Author), Da-Wei Zou (Author), Yan-Bin Gao (Author), Yin-Ying Ba (Author), Jia-Xin He (Author), Zhi-Yao Zhu (Author), Jia-Jun Liang (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tangshenning (TSN) is a safe and effective formula to treat diabetic nephropathy (DN), and clinical studies have demonstrated that its therapeutic effects are related to oxidative stress improvements in patients. Herein, this study aims to explore the potential mechanism of how T...