Development of a fluorogenic ADAMTS-7 substrate

• প্রধান লেখক: Salvatore Santamaria (লেখক), Frederic Buemi (লেখক), Elisa Nuti (লেখক), Doretta Cuffaro (লেখক), Elena De Vita (লেখক), Tiziano Tuccinardi (লেখক), Armando Rossello (লেখক), Steven Howell (লেখক), Shahid Mehmood (লেখক), Ambrosius P. Snijders (লেখক), Rens de Groot (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The extracellular protease ADAMTS-7 has been identified as a potential therapeutic target in atherosclerosis and associated diseases such as coronary artery disease (CAD). However, ADAMTS-7 inhibitors have not been reported so far. Screening of inhibitors has been hindered by the lack of a suitable...