Mathematical modeling of intraperitoneal drug delivery: simulation of drug distribution in a single tumor nodule

• Hoofdauteurs: Margo Steuperaert (Auteur), Giuseppe Falvo D'Urso Labate (Auteur), Charlotte Debbaut (Auteur), Olivier De Wever (Auteur), Christian Vanhove (Auteur), Wim Ceelen (Auteur), Patrick Segers (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The intraperitoneal (IP) administration of chemotherapy is an alternative treatment for peritoneal carcinomatosis, allowing for higher intratumor concentrations of the cytotoxic agent compared to intravenous administration. Nevertheless, drug penetration depths are still limited to a few millimeters...