Chiral separation of (d)- and (l)-enantiomers of doxylamine succinate in rat plasma

• Main Authors: Tadiboyina Sirisha (Author), Bannimath Gurupadayya (Author), Bharathkumar Inturi (Author)
• Format: Knjiga
• Izdano: Faculty of Pharmacy, Cairo University, 2015-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

A selective chiral ultra fast liquid chromatography (UFLC-DAD) method was developed and validated to separate and quantify the (d)- and (l)-enantiomers of doxylamine in rat plasma. After extraction of the plasma samples with acetonitrile, the separation of doxylamine succinate enantiomers and intern...