Mcam Silencing With RNA Interference Using Magnetofection has Antitumor Effect in Murine Melanoma

• Main Authors: Lara Prosen (Author), Bostjan Markelc (Author), Tanja Dolinsek (Author), Branka Music (Author), Maja Cemazar (Author), Gregor Sersa (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The melanoma cell adhesion molecule (MCAM) is involved in melanoma development and its progression, including invasiveness, metastatic potential and angiogenesis. Therefore, MCAM represents a potential target for gene therapy of melanoma, whose expression could be hindered with posttranscriptional s...