Increased apolipoprotein E and decreased TNF‐α in the cerebrospinal fluid of nondemented APOE‐ε4 carriers

• Main Authors: Daimei Sasayama (Author), Kotaro Hattori (Author), Yuuki Yokota (Author), Ryo Matsumura (Author), Toshiya Teraishi (Author), Sumiko Yoshida (Author), Hiroshi Kunugi (Author)
• Format: Book
• Published: Wiley, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim The ε4 allele of apolipoprotein E gene (APOE) is a well‐known risk factor of late‐onset Alzheimer's disease. However, little is known why this variant confers a risk for Alzheimer's disease. The aim of this study was to examine the influence of the APOE genotype on cerebrospin...