Suppressive activity of macrolide antibiotics on nitric oxide production by lipopolysaccharide stimulation in mice

• 主要な著者: Hajime Terao (著者), Kazuhito Asano (著者), Ken-ichi Kanai (著者), Yoshiyuki Kyo (著者), So Watanabe (著者), Tadashi Hisamitsu (著者), Harumi Suzaki (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2003-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background and aim: Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including n...