Suppressive activity of macrolide antibiotics on nitric oxide production by lipopolysaccharide stimulation in mice

• Главные авторы: Hajime Terao (Автор), Kazuhito Asano (Автор), Ken-ichi Kanai (Автор), Yoshiyuki Kyo (Автор), So Watanabe (Автор), Tadashi Hisamitsu (Автор), Harumi Suzaki (Автор)
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• Опубликовано: Hindawi Limited, 2003-01-01T00:00:00Z.
• Предметы: article
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Background and aim: Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including n...