Suppressive activity of macrolide antibiotics on nitric oxide production by lipopolysaccharide stimulation in mice
Background and aim: Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including n...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2003-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Background and aim: Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including nitric oxide (NO), are well recognized as the important final effector molecules in the development and the maintenance of inflammatory diseases. |
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| Item Description: | 0962-9351 1466-1861 10.1080/09629350310001599620 |